Search results for " stainless steel"
Article
Advancing Single-Use Technology Through Collaboration
…e next five years to a point that is either equal to or better than the knowledge and application of stainless steel today, and the current article shares insights from three of those members.
St…
Article
Modeling Bioreactor Performance
Model effectiveness is determined by the quality and composition of the data inputs.
By Cynthia A. Challener
Bioreactor design, including the geometry of the tank and impeller and the locati…
Article
Cleaning of Dedicated Equipment: Why Validation is Needed
Equipment can be considered as “cleanable” if it is constructed using adequate materials such as stainless steel or polymeric materials that are compatible with the process to be carried out. Finished…
Article
Advanced Technologies Facilitate Scale-up and Technology Transfer
“Because these cultures require very good heat removal, high oxygen transfer, and other rigorous conditions, stainless steel tends to remain the best possible option for microbial processes today,” he…
Article
Continuous Chromatography: Trends, Definitions and Approaches
Continuous operation can be performed using standard stainless steel systems without problems and potentially at a lower cost. For instance, in the early days of implementation of SUS, an argument was…
Article
Continuous Manufacturing: A Changing Processing Paradigm
Apr 01, 2015
By Randi Hernandez
BioPharm International
Volume 28, Issue 4
Although continuous manufacturing is well established for bulk chemicals, complex automation and validation …
Article
Securing the Single-Use Supply Chain
In the past, when drugs were manufactured in stainless steel, the manufacturer was in control of the infrastructure once its facility was in place, sourcing only critical disposable components such as…
Article
Single-Use and Continuous Processing Technologies Change Facility Design
With stainless steel, duplicate equipment is needed to prepare one column step offline for the next campaign. With SU, however, new equipment is put in place with little preparation required.
In t…
Article
A Q&A With Parrish Galliher About Adopting Single-Use Systems
How will increased adoption of single-use impact the industry?
On a commercial level, it will save companies a lot of capital compared to stainless steel facilities. Since 90% of drugs fail during…
Article
The use of Xcellerex™ mixing system as slurry tank when packing chromatography columns
This application note describes the performance of single-use Xcellerex XDM Quad Mixing System used as a slurry tank when packing chromatography columns. The capability of the mixing system to keep …