Search results for " viral vectors" in Articles / App Notes
Article
What’s New in Upstream Technologies
The system features a modular, scalable, fixed-bed bioreactor for enhanced upstream processing of viral products, including viral vaccines, viral vectors, and oncolytic viruses. The low-footprint inte…
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Science Focus Fuels Successful Process Development for Startups
Getting the science right helps biopharma startups overcome development and commercialization challenges.
By Cynthia A. Challener
sdecoret/Stock.Adobe.com
Pr…
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Developing an Efficient Adenovirus Downstream Purification Process
Adenovirus is one of the most frequently used viral vectors in the development of therapeutic vaccines and adenovirus is evaluated as vaccine delivery system in many preclinical and clinical studies…
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Achieving Efficient Adenovirus Upstream Production
Adenovirus is one of the most frequently used viral vectors in the development of therapeutic vaccines and vaccines against infectious diseases. Adenovirus has also been explored as a viral vector f…
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Report from the 6th International HTPD Conference
The biggest challenge is still the people and Quantitative Structure-Activity Relationship (QSAR) plus mechanistic modeling were two key take-home messages from the 6th International conference devote…
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Webcast: Repeatable, automated SPR titer assay for adeno- and adeno-associated viruses in crude samples
Viral vectors are commonly used in clinical trials to evaluate gene therapies. Due to instability, these vectors are difficult to produce and analyze. Current assays lack the sensitivity requi…
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Scalable AAV Production Process for Gene Therapy
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Viral vectors are often used for gene transfer of specific tissue- or cell-type modifications. Several viruses have been investigated for use in cell and gene therapy; adeno-associ…
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2019’s Top Bioprocessing Trends and What to Expect in 2020
Following the high interest in cell and gene therapies, there is a big interest in viral vectors, especially for adeno-associated virus, but also adenovirus. In 2019, a novel production process for ad…
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Evaluation of HEK293 Cell Growth and Adenovirus Productivity in HyClone™ CDM4HEK293 Medium
HEK293 cells are susceptible to infection by adenovirus, one of the most frequently used viral vectors in the development of therapeutic vaccines and vaccines against infectious diseases. This applica…
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Milestones and Moderate Progress in 2012 Drug Approvals
First gene therapy and plant-based expression vector products approved in 2012.
In terms of product approvals, the past year can be considered reasonably successful. Twelve biopharm…