Search results for "messenger RNA"
mRNA: The Messenger - mRNA Synthesis
Explore the mRNA universe with Cytiva. Join us for part 3 of mRNA: the messenger, where we discuss key considerations for the synthesis of RNA molecules, including optimizing the…
Enhancing Resins Addresses Purification Concerns
What COVID-19 brings to the table The COVID-19 vaccines comprise several possible and different modalities, such as messenger RNA (mRNA), attenuated viruses, viral vectors, proteins, and virus l…
Can Vaccine Development Be Safely Accelerated?
Prophylactic messenger RNA vaccines Two companies, both also supported by grants from CEPI, have developed platform technologies based on messenger RNA (mRNA). Cambridge, MA-based Moderna—which ha…
A Risk-Based Genetic Characterization Strategy for Recombinant CHO Cell Lines Used for Clinical and Commercial Applications
…ss in mammalian cells that removes introns and joins exons in a primary transcript to create mature messenger RNA (mRNA) for translation. For biopharmaceutical development, the recombinant genes codi…
Genetic Vaccine Platforms Demonstrate Their Potential
Genetic vaccines include messenger RNA (mRNA)/DNA. Alternatively, vaccines can be classified into live and non-live vaccines, which is important when considering safety profiles. Traditional v…
Discussing the Origins of the mRNA Therapeutics Field
Andy Geall, co-founder and chief development officer at Replicate Bioscience, discusses the historical context and buildup of the mRNA therapeutics field. Watch video
Need solutions for large-scale production of mRNA-based molecules?
Therapies based on messenger RNA, such as mRNA vaccines, have revolutionary potential. mRNA therapeutics offer precise and individualized therapy and avoid manufacturing issues associated wit…
Top Process Development Trends for 2021 and a Look into 2022
However, the focus in 2021 shifted beyond the pandemic to optimization and scaling up adeno-associated virus (AAV) production, process workflows and considerations for messenger RNA (mRNA) therapeutic…
Maximum Output Starts with Optimized Upstream Processing
… first authorized candidates are based on adenoviral technology (AstraZeneca/Oxford and Janssen) or messenger RNA (mRNA) (Pfizer-BioNTech, Moderna), with candidates still in development being DNA-bas…
mRNA Processing Workflow for Vaccines and Therapeutics
CLICK HERE TO VIEW >> Learn more on key considerations when setting up a messenger RNA (mRNA) process with this infographic.