Search results for " Hydrophobic interaction chromatogr…"
Article
Protein Purification Troubleshooting Guide
Practical advice to significantly impact your chromatography workflow
Put this poster on your lab wall to quickly identify and resolve protein purification problems when and where they happen. I…
Article
Optimization of a HIC step for recombinant protein purification
Follow this step-by-step high-throughput process development (HTPD) workflow to determine the optimal resin and initial conditions for hydrophobic interaction chromatography (HIC).
…
Article
Webinar: Optimizing a HIC step with HTPD
Webinar date: Wed, Mar 8, 2023 11:00 AM EST (5:00 PM CET)
This webinar discusses a step-by-step workflow for optimizing a hydrophobic interaction chromatography (HIC) step.
Thi…
Article
Recent Advances in the Use of Exoglycosidases to Improve Structural Profiling of N-glycans from Biologic Drugs
C) Digested N-glycans are separated by UHPLC coupled to fluorescence detection (FLR) using hydrophobic interaction chromatography (HILIC), and monosaccharide removal events are visualized by peak shif…
Poster
Fast Trak Services: a collaborative project to accelerate downstream biosimilar process development
Process optimization focused on improving the affinity chromatography (AF) capture step as well as the intermediate purification and polishing steps, using hydrophobic interaction chromatography (HIC…
Article
Developing a HIC polishing step for removal of mAb aggregates
This article describes the development of a flow-through (FT) polishing step using hydrophobic interaction chromatography (HIC) to remove mAb aggregates.
It includes:
- The use of HTPD plate…
Article
Your Protein Purification Questions Discussed
In one of Cytiva´s web chats, ÄKTA™ system users asked questions relating to lab-scale protein purification and ÄKTA systems, which experts answered during a live session.
The expert…
Article
Mechanistic Modeling: Does it Have a Future in Process Development?
The application of mechanistic models for process development and optimization has been a topic of discussion in the pharmaceutical industry for many years. Mechanistic models are considered as an a…
Webcast
Optimizing a HIC step with HTPD
This webinar discusses a step-by-step workflow for optimizing a hydrophobic interaction chromatography (HIC) step.