Search results for "Plasma" in Articles / App Notes
Article
Recent Advances in the Use of Exoglycosidases to Improve Structural Profiling of N-glycans from Biologic Drugs
Co-migrating isomers are especially evident in complex samples such as serum (3) or plasma (4), in which a single UHPLC-FLR peak may contain over five glycan species with the same mass. In all samples…
Article
Ensuring Viral Safety of Viral Vaccines and Vectors
UV-C irradiation has been used in the food, plasma, and biotech industries (for packaging and surface sterilization) and is effective against various biological contaminants, including bacteria and vi…
Article
Putting Viral Clearance Capabilities to the Test
“This is of specific concern for biopharmaceuticals directly isolated from human or animal tissues, like human plasma products. On the other hand, the laboratory model viruses have a great chance of c…
Article
Biopharmaceutical Market in Asia: Q&A with Günter Jagschies, Strategic Customer Relations Leader, Cytiva
Specific topics will be the review of health challenges in Asia and future approaches to address them, creative technology solutions, facility and regulatory aspects, as well as vaccines and plasma de…
Article
Managing Residual Impurities During Downstream Processing
…replace traditional wet chemistry techniques for heavy-metal determination with inductively coupled plasma mass spectrometry (ICP-MS) in a risk-based approach for monitoring levels of potential eleme…
Article
Fusion Proteins Pose Manufacturability Challenges
“In particular, the level of N-acetylneuraminic acid or sialylation, which can impact plasma half-life and the potency of the candidate, is a key quality attribute and can be challenging to control wi…
Article
Improving Process-Scale Chromatography
She points to several new types of affinity chromatography resins introduced to the market in recent years that target recombinant plasma proteins, gene therapy applications, and different types of an…
Article
Affinity chromatography Handbook - Vol. 3: Specific Groups of Biomolecules
Affinity chromatography (AC) separates proteins on the basis of a reversible interaction between a protein (or group of proteins) and a specific ligand coupled to a chromatography matrix. The techni…
Article
Biopharma in 2015: A Year for Approvals and Innovations
… capacity using single-use versus stainless steel fermentation equipment
A Bright Future for the Plasma Fractionation Industry
Defining Critical Quality Attributes for Monoclonal Antibody Thera…
Article
Ensuring the Quality of Biologicals
Biologicals are those products derived from biological sources such as tissues and cell extracts, fermentation using micro-organisms, plasma, plants, or those produced by recombinant DNA technology. T…