Search results for " biomanufacturing"
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Tools for Continuous Bioprocessing Development
For the needs of conventional biomanufacturing, these cultivation modes are sufficient. However, continuous culture operation, in all its forms--chemostat, turbidostat, and perfusion--can support meta…
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Improving mAb Manufacturing Productivity by Optimizing Buffer and Media Prep Process Flow
The increase in titers and the trend toward continuous biomanufacturing will lead to increased demand in buffer volumes and prep times. To address this gap, strategies for improving mAb manufacturing …
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Improving Upstream Predictability
Some of the most significant gains have been made in cell line expression, advanced sensors, and automation, says Atul Mohindra, R&D director for biomanufacturing at Lonza Pharma and Biotech. “Using a…
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Monitoring and Control of Inline Dilution Processes
Inline dilution (ILD) combined with inline conditioning (IC) is one of the key ways to intensify downstream processes, according to Avril Vermunt, program manager for connected biomanufacturing at Cyt…
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Reconciling Sensor Communication Gaps
To manage these complexities, Emerson is betting on augmented reality—a technology under evaluation in the oil and gas industry—which the company believes could help the design and validation of bioma…
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Downstream Processing Continues to Worry CMOs
Conclusion
Data show that downstream purification continues to worry the biomanufacturing industry. Downstream problems, however, are contributing to more serious bottlenecks for CMOs than for bio…
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Gene Therapies Push Viral Vector Production
At Cytiva, the company offers a structural solution to increasing viral vector manufacturing capacity through its KUBio box, a modular biomanufacturing environment. The company has tailored its KUBio …
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How the Industrial Internet of Things is Transforming Bioprocessing
He also discusses how the centralization of data enables analytics and artificial intelligence to improve productivity and process understanding in biomanufacturing.
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Four Steps Toward End-to-End Connected Manufacturing
Continuous biomanufacturing is a key step toward promoting drug quality and improving manufacturing productivity, leading to lower drug prices.
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The Challenge of Disruptive Technologies in Bioprocessing
… the growing R&D expenditure in biopharma companies are factors driving the growth of the global biomanufacturing industry, including downstream bioprocessing,” adds Orjana Terova, product manager, d…