Search results for "process intensification"
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Making the Move to Continuous Chromatography
“Even though regulatory agencies are very supportive and collaborative when it comes to companies introducing different process intensification initiatives, there is still, to my knowledge, no approve…
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Reducing Cross-Contamination Risks in Process Chromatography
Advances in single-use technology are, in fact, facilitating process intensification and continuous processing.
Continuous chromatography is a technique that many facilities are currently…
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Optimizing Late-Stage and Commercial Cell-Culture Processes
• Increased focus on implementation of single-use technologies and process intensification.
• Increased process complexity to achieve higher productivities.
• Targeted integration cell-l…
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Scaling Up Novel Therapies
“Process intensification will enable much quicker pull through of personalized medicines, especially gene therapies and eventually cell therapies,” says Rick Morris, senior vice-president of product d…
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Unifying Continuous Biomanufacturing Operations
Process intensification and the use of high-seed cultures, coupled with continuous methods, allows manufacturers to produce the same quantity of protein as pilot-scale resources in half the time. Benc…
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Maximum Output Starts with Optimized Upstream Processing
“The latest iteration of technologies is being developed with scalability, process intensification, and lean principles in mind to ensure quality and reliability for the life of a process,” he asserts…
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Biomanufacturing: Demand for Continuous Bioprocessing Increasing
Therefore, the industry continues to seek solutions from innovators for better continuous processes that offer further process intensification and lower costs. In fact, 70.6% of bioprocessing professi…
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Improving Upstream Predictability
In response to extreme cost pressures, companies are using or considering process intensification at every stage of upstream processing, says Andreas Castan, also strategic technology partnerships lea…
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Enhancing Resins Addresses Purification Concerns
Christoph Burgstedt/Stock.Adobe.com
Enhancement of resin technology can improve the ability of chromatography to purify the growing landscape of increasingly complex biomolecu…
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Downstream Processing for Cell-Based Therapies
By Qasim A. Rafiq, Fernanda Masri
With increasing numbers of advanced therapies—including cell and gene therapies—entering early- and late-stage clinical development, significant focus has been …