Search results for "Mechanistic modeling; process devel…"
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Adsorption isotherm models for chromatography
Read on commonly used models for the thermodynamics of adsorption within a chromatography column.
Indeed, in order to create a complete chromatography model, the adsorption of compon…
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Simulating chromatography processes in the growing molecular diversity
The increasing complexity and diversity of development pipelines poses new challenges for product manufacturing. Mechanistic modeling can play a key role in overcoming these challenges as they…
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Mechanistic chromatography modeling in practice
Access insider recommendations for getting started with mechanistic modeling of chromatography, but also case studies and scientific publications.
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How do mechanistic chromatography models work?
This knowledge hub contains animations, articles, and webinars to explain what mechanistic modeling is, its benefits, and how it works.
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Mechanistic chromatography models in a nutshell
Find out how mechanistic modeling simulates what happens in your chromatography columns.
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Understanding fluid dynamics within a chromatography column
See how fluid flow effects within a chromatography column are used by mechanistic models.
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Mechanistic Modeling of Chromatography: Opportunities and Challenges
What is mechanistic modeling in chromatography? Explore opportunities and challenges of an approach that can help make process development become faster, more scientific, and more reliable.
Cl…
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Digitalization: The Route to Biopharma 4.0
Industry 4.0, also known as the Fourth Industrial Revolution (4IR), will result in the digital transformation of the manufacturing sector. It is propelled by transformative trends such as the prolif…
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QbD and PAT in Upstream and Downstream Processing
To gain perspective on the implementation of quality by design (QbD) and process analytical technology (PAT) in biopharmaceutical processing, BioPharm International spoke with Clinton Weber, as…
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Addressing the Complex Nature of Downstream Processing with QbD
Quality by design brings both challenges and benefits to the development of downstream processes.
By Susan Haigney
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Regulators have been en…