Search results for " efficiency" in Articles / App Notes
Article
Efficient purification of meningococcal polysaccharides in a two-step chromatography workflow
This application note demonstrates the purification of meningococcal capsular polysaccharides using chromatography. The described process constitutes a viable alternative to the traditional proce…
Article
Efficient Purification of the Pertussis Antigens Toxin, Filamentous Haemagglutinin, and Pertactin in Chromatography Workflows
This application note describes the purification of pertussis toxin (PT), filamentous haemagglutinin (FHA), and pertactin (PRN) in a process based on modern chromatography resins. The described meth…
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Efficient Purification of Pneumococcal Polysaccharides in a Chromatography Workflow
This application note demonstrates the purification of pneumococcal capsular polysaccharides using chromatography. The described process constitutes a viable alternative to the traditional process f…
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Making the Move to Continuous Chromatography
Switching from batch to continuous allows for improved resin capacity utilization through continuous loading (overloading, in fact) of the column or membrane for increased process efficiency. It is pa…
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Operational Excellence: More Than Just Process Improvement
Life-sciences companies face more pressure than ever to reduce costs and increase efficiency. The pressures are many and relentless: price constraints, global competition, product complexity, and more…
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Updating Viral Clearance for New Biologic Modalities
“As we look at new technologies for improving the efficiency of molecule separation, we always evaluate them based on their ability to remove a virus,” Verlenden says, noting that most downstream temp…
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Technology Innovations Improve Process Chromatography Performance
He adds that variability in raw materials can present serious issues that impact downstream efficiency and can lead to long investigations and potential delays in making drugs available for patients. …
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Process Chromatography: Continuous Optimization
Drug manufacturers are always seeking ways to improve the efficiency and productivity of chromatographic separations. Suppliers of chromatography resins are developing new resin chemistries and bindin…
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Digitalization: The Route to Biopharma 4.0
… reduce human intervention, automate process control, and perform fault detection to improve process efficiency.
However, there are many attributes such as charge variant, aggregates, host-…
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Enhancing Resins Addresses Purification Concerns
“Although the purification challenges for each modality are different, all downstream processes have the common goal of increasing yields with process efficiency in a cost-effective way while ensuring…