Search results for " Wave"
Article
Adherent Cell Culture in Biopharmaceutical Applications: The Cell-Detachment Challenge
In this type of substrate, a transient hyperthermic effect results from the interaction of light of a given wavelength with nanoparticles integrated in the support. To date, available systems were bas…
Article
Tools for Continuous Bioprocessing Development
For example, perfusion process development experiments (21) using a 4-L working-volume Wave bag and alternating tangential flow (ATF) or tangential flow filtration (TFF) cell-retention filter, consume…
Article
Biopharma in 2015: A Year for Approvals and Innovations
…essing of a monoclonal antibody
Highly efficient inoculum propagation in perfusion culture using WAVE Bioreactor™ systems
The Use of Dynamic Control in Periodic Counter-Current Chromatography
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Article
Implications of Cell Culture Conditions on Protein Glycosylation
The authors present a review of the techniques commonly used for glycosylation analysis.
By Michiel E. Ultee, PhD, Dr. Richard Easton
This article reviews the implications of cell-culture co…
Article
Taking a “Development-by-Design” Approach to Cell Therapies
Cytiva is also evaluating Wave and other systems and set up a center of excellence in Wales recently.
In other equipment areas, Pall Corp. has been partnering with CMDG LLC on cord blood processin…
Article
The Bullish Outlook for Biosimilars
Despite the slow pace of its regulatory development, the US appears to be getting close to its first wave of biosimilars, pending ongoing patent disputes. A few months ago, FDA accepted Sandoz’s and C…
Article
Implementation of Raw Material Control Strategies in the Manufacture of Single-Use Bioprocessing Containers
The containers were attached to a WAVE Bioreactor 20/50 EHT system (Cytiva) and inflated with air, after which inlet and outlet filters were clamped off to create a contained incubation system. ActiCH…
Article
What Drove Biopharma Development in 2014?
On the PDF site, this trend was evident based on webinar invitations, as well as in published application notes and articles, such as Highly efficient inoculum propagation in perfusion culture using W…
Article
Trends in Single-use Bioreactors
One example is the ReadyToProcess WAVE 25 bioreactor system that can be used with disposable Cellbag chambers designed for perfusion with an internal floating filter. This allows a small-scale continu…
Article
Using Quality by Design to Develop Robust Chromatographic Methods
Figure 5 represents the experimental region from the first wave of experimental design studies (DoE-1). This design included the following parameters which were identified during the risk assessment a…