Search results for " media"
Article
Understanding and Controlling Raw Material Variation in Cell Culture Media
Manage variability through advanced analytical methods and risk-based assessment.
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Poster
Purification of monoclonal antibodies using modern chromatography media and membranes
This white paper is a guide to the development of MAb purification platforms and provides an overview of Cytiva’s offering of process chromatography media (resins) and membranes for MAb purification…
Article
Concentrating Feed—an Applicable Approach to Improve Antibody Production
By raising the pH or by adding surfactants, the feed media could be concentrated by 1.3- to 2.5-fold. These approaches did not affect product quality and were effective for multiple cell lines and app…
Article
Achieving Process Balance with Perfusion Bioreactors
Perfusion processes are generally considered to be those in which the product is continuously harvested from the bioreactor and new media is fed. These processes can be run for weeks or even months at…
Article
Perfusion in the 21st Century
Manufacturers have access to more sophisticated media and more stable cell lines with new selection technologies that eliminate the need to use expensive selection agents that are required for selecti…
Article
Optimizing Resin Performance with Disposable Chromatography Solutions
…öm, product manager, Cytiva; Jonathan Royce, bioprocess senior product manager of antibody affinity media, Cytiva; and Steve Tingley, vice-president of sales and marketing, bioprocessing, Repligen ab…
Article
Optimizing your Cell Culture Process to Improve Productivity
The companies that support biopharma’s such as contract manufacturing organizations or CMOs are participating in cell line or media development. We have been working with cultured meat industry, which…
Article
Single-Use Technologies Prove Effective for Viral Vector Process Development
Automated bioreactors, Cameau adds, provide opportunities for optimization with regard to the cell-culture media/surface ratio in adherent processes. “Compared to flatware, the ratios in fixed-bed bio…
Article
Improving Upstream Predictability
Today, better understanding of cells and how they interact with their environment has enabled improvements in most aspects of upstream processing, from bioreactor design and media development to proce…
Article
An Integrated Approach to Ensure the Viral Safety of Biotherapeutics
Cell-culture applications are impossible without the use of nutrient media for cell multiplication and subsequent product generation. Although several serum-free and chemically defined nutrient media …