Search results for " Mabs"
Article
Technical and Process Economical Aspects of Using Capto™ Q and ReadyToProcess™Adsorber Q in mAb Polishing
Increasing product titers in upstream cell culture processes pose challenges to downstream purification processes. For efficient operations, downstream purification needs to be able to handle high p…
Poster
Optimizing dynamic binding capacity and aggregate clearance in an mAb polishing step
Capto™ S ImpAct is a strong cation exchange (CIEX) chromatography medium (resin) designed for monoclonal antibody (MAb) polishing steps. In this study, optimization of binding conditions targeting h…
Article
Exploring the world of antibodies: mAbs, Fabs, dAbs, and bsAbs
Developing purification processes for antibody variants is not always straightforward and the platform approaches conveniently used for many traditional mAbs cannot be used.
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Article
A Small-Scale Model to Increase Yield in Cell Culture Perfusion of mAb at Large Scale
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As process intensification is adopted into large-scale manufacturing, the responsibility on scale-down models to accurately represent the expanded operating space quickly follow…
Resource
Accelerate mAb Process Development with Fibro Rapid Cycling Chromatography
Results in minutes, not hours: That’s one of the ways protein A fiber chromatography opens new opportunities in downstream process development for mAbs. In this webcast, Cytiva experts discuss how y…
Article
WEBCAST ON DEMAND: Accelerate mAb Process Development with Fibro Rapid Cycling Chromatography
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Results in minutes, not hours: That’s one of the ways protein A fiber chromatography opens new opportunities in downstream process development for mAbs. In this webcast, Cytiva e…
Article
A Small-Scale Model to Increase Yield in Cell Culture Perfusion of mAbs at Large Scale
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We have developed a reliable small-scale model for a monoclonal antibody (mAb) perfusion process using TPP® TubeSpin® Bioreactor tubes and the ReadyToProcess WAVE 25 R…
Article
Scaling a mAb Production Process to Xcellerex Bioreactors
This article discusses moving a monoclonal antibody (mAb) production process from a microscale bioreactor to the Xcellerex XDR single-use platform.
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Article
Case Study: High Throughput mAb Purification Using Fibro
In this case study, a drug discovery lab at AstraZeneca finds that purifying antibodies with Fibro PrismA means they can screen more candidates per week with a simpler equipment setup.
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Article
Addressing mAb Purification Bottlenecks with Rapid Cycling Chromatography
Fibro chromatography is a recently launched chromatography platform that enables purification cycles in minutes rather than hours. The rapid purification enables higher throughput in research and pr…