Search results for "pDNA"
Article
Enhancing Resins Addresses Purification Concerns
Deorkar also explains that plasmid DNA (pDNA) and recombinant adeno-associated viruses (rAAvs) are two other classes of biologic molecules that are of high interest for the biopharmaceutical industry …
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Akron Bio Will Install a Cytiva FlexFactory to Manufacture Plasmid DNA
Cytiva will provide its FlexFactory, a flexible, single-use platform, to enable Akron Biotech to manufacture plasmid DNA (pDNA), which is used in many innovative therapies and vaccines, Cytiva said in…
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A Look at the Affinity Chromatography Landscape
He points to the use of conventional, non-porous particles in amino acids–DNA affinity chromatography for the purification of super-coiled plasmid DNA (sc pDNA) as an example. “Using amino acid affini…
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A scalable single-use two-step plasmid purification process
While MAb processes have become much more efficient, production of mRNA and viral vectors is still hindered by the requirement for a reliable source of high-quality plasmid DNA (pDNA), which typically…
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Single-use Bioreactors Have Reached the Big Time
…t also dramatically reduce the footprint required to produce the virus titers, and it requires less pDNA to transfect the cells, according to Onraedt. “Single-use bioreactors such as the iCELLis allo…