Viral vaccines need to be produced fast and in large quantities. Routine immunizations and preventive campaigns, like stockpiling in response to emergencies, involve millions of doses, and speed is essential. Shortening the time to market is beneficial for both the manufacturer and the patient. Design of experiment (DoE) is an important part of the work. The approach helps determine which components in the media will have the most beneficial effect on cell growth. Surface Plasmon Resonance (SPR) analysis during process development provides data about virus behavior and host interactions. This is valuable both for regulatory compliance and future drug development.
June 6, 2019
Faster Flavivirus Vaccine Production