Comparison of Three Different Screening Techniques…
November 7, 2019 - Screening of chromatographic conditions can be done in several ways, such as 96-well plates, mini-columns, and tips. It is important that …

Many Ways to Improve Productivity
September 26, 2019 - Bill Whitford, Alain Sourabié, Procelys by Lesaff… Means of productivity improvement range from increasing specific productivity of microbial or animal cells to improvements in the facility…

A Scalable Adenovirus Production Process, from Cel…
July 18, 2019 - Åsa Hagner-McWhirter, Gustaf Ahlén, Magnus Bergm… Adenovirus (AdV) vectors are commonly used in cancer gene therapy trials and evaluated for use in vaccines for various diseases. In this stu…

Reduce Risk of Failure in Your Virus Clearance Stu…
July 18, 2019 - Tina Pitarresi and Linnea Troeng Effective viral clearance studies remain one of the challenges facing manufacturers of biologics. These studies are an essential part of p…

Animal Component-Free Rotavirus Production Using M…
July 2, 2019 - Ann-Christin Magnusson, Christine Sund-Lundström,… Rotavirus (RV) disease is a significant cause of diarrhea in children and a serious issue in developing countries. There are a number of RV …

Perfusion Media Development for Scalable Processes
July 2, 2019 - Patrick Mayrhofer (1), Andreas Castan (2), Renate … Cell culture perfusion processes are considered optimal for a truly integrated continuous biomanufacturing pipeline. The nutrient-rich but b…

Scaling In-Line Buffer Preparation from Process De…
May 23, 2019 - Karolina Busson, Enrique Carredano, Jenny Dunker, … Preparing buffers for large-scale chromatography requires significant resources: time, money, and storage space. Inline conditioning (IC) is…

To Speed Up the Process Optimization of the Descri…
March 18, 2019 - Sushma Nayak Teichert, Anna Maria Gudmundsdottir, … When establishing purification processes for a biosimilar molecule it is important to develop steps that are scalable, selective and cost …

Single-Step, Protein A Chromatography Process for …
January 31, 2019 - Bengt Westerlund, Tomas Björkman, Anna Mattsson, … A single‑step downstream process using protein A chromatography to purify a bispecific antibody (BsAb) in early screening has been succe…

High-Throughput Downstream Processing Using Cellul…
January 18, 2019 - Ian Scanlon, Oliver Hardick, Peter Guterstam, Linn… Developing a process or looking for a clone of interest often requires screening large numbers of samples. Many analyses require purified pr…

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