Comparison of Three Different Screening Techniques…
November 7, 2019 - Screening of chromatographic conditions can be done in several ways, such as 96-well plates, mini-columns, and tips. It is important that …

A Scalable Adenovirus Production Process, from Cel…
July 18, 2019 - Åsa Hagner-McWhirter, Gustaf Ahlén, Magnus Bergm… Adenovirus (AdV) vectors are commonly used in cancer gene therapy trials and evaluated for use in vaccines for various diseases. In this stu…

Reduce Risk of Failure in Your Virus Clearance Stu…
July 18, 2019 - Tina Pitarresi and Linnea Troeng Effective viral clearance studies remain one of the challenges facing manufacturers of biologics. These studies are an essential part of p…

Perfusion Media Development for Scalable Processes
July 2, 2019 - Patrick Mayrhofer (1), Andreas Castan (2), Renate … Cell culture perfusion processes are considered optimal for a truly integrated continuous biomanufacturing pipeline. The nutrient-rich but b…

Scaling In-Line Buffer Preparation from Process De…
May 23, 2019 - Karolina Busson, Enrique Carredano, Jenny Dunker, … Preparing buffers for large-scale chromatography requires significant resources: time, money, and storage space. Inline conditioning (IC) is…

To Speed Up the Process Optimization of the Descri…
March 18, 2019 - Sushma Nayak Teichert, Anna Maria Gudmundsdottir, … When establishing purification processes for a biosimilar molecule it is important to develop steps that are scalable, selective and cost …

High-Throughput Downstream Processing Using Cellul…
January 18, 2019 - Ian Scanlon, Oliver Hardick, Peter Guterstam, Linn… Developing a process or looking for a clone of interest often requires screening large numbers of samples. Many analyses require purified pr…

Opportunities, Challenges, and Economic Drivers fo…
December 6, 2018 - Avril Vermunt, Andreas Castan, Oliver Hardick, Mag… Continuous unit operations have been used successfully in manufacturing of several approved products with a collective revenue of $25 bill…

Scalable Continuous Chromatography Process for Enh…
November 20, 2018 - Linda Mathiasson*, Linda Persson*, Mikael Berg*, M… The cost pressure on biopharmaceuticals drives the industry toward exploring process intensification options that will maintain or improve…

A Scalable Adenovirus Production Process
September 13, 2018 - Åsa Hagner-McWhirter, Gustaf Ahlén, Magnus Bergm… The promising results from clinical studies on the use of viral vectors to address important medical needs have spurred interest in develo…

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