Search results for " sample prep"
Article
Purifying Samples for Cryo-EM Preps
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Technical improvements in cryogenic electron microscopy (cryo-EM) have triggered a revolution in structural biology and made single-particle cryo-EM …
Article
Improving mAb Manufacturing Productivity by Optimizing Buffer and Media Prep Process Flow
Innovative approaches, including ready-to-use materials and in-line dilution, can significantly streamline overall bioprocessing operations.
By: Pranav Vengsarkar and Nandu Deorkar
I…
Article
Walk Away and Do More Screening Preps
Developing a process or looking for a clone of interest often requires screening large numbers of samples. Many analyses require purified protein, and substantial hands-on time might be allocated to…
Article
Modeling the Degradation of mAb Therapeutics
Aggregate sample prep and characterization
To monitor and understand the aggregation mechanism and its behavior in proteins, a model protein (mAb) was chosen with an isoelectric point (pI) of 8.5.…
Article
Design of Experiments for Analytical Method Development and Validation
The measurement process is made up of methods, standards, software, materials, chemistry, reagents, analysts, sample preparation methods, environmental conditions, and instrumentation/equipment. Quali…
Article
Understanding Protein Production from Start to Finish
Most scientists working with exploring proteins and developing specific target biomolecules use several steps including cell culture, sample preparation, purification, and analysis. This requires unde…
Article
Continuous Processing for the Production of Biopharmaceuticals
The authors review the technologies that may help bioprocessing become a truly continuous operation and present case studies that could contribute to the integration of upstream and downstream platf…