Search results for "PAT"

Article Moving PAT from Concept to Reality
PAT is not only enabling, but essential, to continuous bioprocessing. With sufficient advances, emerging PAT solutions should ultimately make real-time release testing possible. In-line, at-line, …

Article Improving PAT for Biologics
…D) approach to pharmaceutical manufacturing is the implementation of process analytical technology (PAT) for ongoing monitoring and adjustment of production processes to ensure the production of biol…

Article QbD and PAT in Upstream and Downstream Processing
Some of these CQAs, such as glycoxylation pattern for monoclonal antibody (mAb) products, are primarily impacted by the upstream process and are particularly important to monitor during process develo…

Article The Importance of Process Intensification and PAT for Achieving Real-Time Release
Those process analytical technologies (PAT) are a critical part of control strategies that ensure continuous operation within the design space. While …

Article Leveraging Data for Better Biopharmaceutical Process Control
For many years, though, extending this approach into true process analytical technology (PAT) and using it to track and control processes was done mainly in the research lab. Recently, there ha…

Article The Lifecycle Change of Process Validation and Analytical Testing
Jones (Innopharma Labs): A manufacturer can only truly understand their process and successfully demonstrate continued process verification through the implementation of process analytical testing (PA…

Article Remote Monitoring and Big Data Advance Upstream Automation
“Connected, continuous, and process analytical technology (PAT) solutions that bring more process intelligence and quality decisions to the factory floor are becoming more common,” asserts Marc Sincla…

Article Analytical Considerations for Successful Upstream Process Development with Spivey and Lane
…ell perfusion  7:16 - Critical process parameters and CQA 9:25 - PAT  10:35 - Continuous manufacturing  Transcript BioPharm Internatio…

Article Single-Use Technologies Prove Effective for Viral Vector Process Development
For single-use systems in particular, Sanderson adds that cell-culture compatibility is critical because many of the plastics and polymers used in biologics manufacturing are not inert to biological p…

Article QbD Improves Cell-Culture Process Control
Real-time quality control Integrating process analytical technology (PAT) into the bioproduction process enables the biomanufacturer to move from a quality-by-testing approach to a QbD approach, w…

Next Page