Search results for " mRNA"
mRNA Therapeutics and Vaccines – Key Process Considerations
Click here >> Learn more on key considerations and strategies for process development and scaling up in our new web hub for mRNA therapeutics and vaccines.
mRNA Processing Workflow for Vaccines and Therapeutics
CLICK HERE TO VIEW >> Learn more on key considerations when setting up a messenger RNA (mRNA) process with this infographic.
mRNA Vaccines: Current Trends and Perspectives
There are still challenges to overcome to fully realize the potential of this technology, but the COVID-19 pandemic publicly demonstrated the promise of mRNA therapies. The future looks bright for thi…
Increasing mRNA Capabilities and Capacity for Growing Market Needs
Click here to read more >> The success of the mRNA vaccine market is fueling high demand for mRNA, resulting in a critical need to address the manufacturing bottlenecks.
Genetic Vaccine Platforms Demonstrate Their Potential
Genetic vaccines use part of the virus’ own genetic code (either mRNA or DNA) to instruct cells to make a viral antigen that will stimulate an immune response. Viral-vectored vaccines allow selection …
Can Vaccine Development Be Safely Accelerated?
Cambridge, MA-based Moderna—which has developed numerous prophylactic mRNA vaccines with positive Phase I clinical readouts and also has a fully integrated clinical-material manufacturing site—is prog…
A Risk-Based Genetic Characterization Strategy for Recombinant CHO Cell Lines Used for Clinical and Commercial Applications
Evaluation of integrity of the transgene mRNA expressed in CHO cells RNA splicing is a natural process in mammalian cells that removes introns and joins exons in a primary transcript to create matu…
Maximum Output Starts with Optimized Upstream Processing
Innovation in storage and distribution was evident with the mRNA vaccine roll-out, Bottone adds. “Modular and mobile solutions will be important for scale-up and capacity-expansion opportunities with …
Future Downstream Process Development Solutions for Advanced Therapies
downstream Click here to view more Industry Leader Q&As >> Peter Guterstam, PhD, Product Manager of Next Generation Resins & Technologies at Cytiva, provides insight into solutions for ad…
Techniques for Improving Process Development for Exosome-Derived Therapeutics
One cancer treatment with enormous potential is for exosomes to deliver siRNA and knock down the expression of oncogenic mRNA. The laboratory of Dr. Raghu Kalluri, one of our founders at The Universit…