Search results for "virus" in Articles / App Notes
Article
Overview of a scale-up of a cell-based influenza virus production process using ReadyToProcess equipment
…p of upstream and downstream processes for the production of a cell based live attenuated influenza virus using single-use ReadyToProcess technology (Fig 1).
Introduction
Egg-based produc…
Article
Virus safety challenges: get the job done!
In this free 1-day seminar you’ll learn how to conduct virus filterability trials, including prefiltration.
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Article
Validation of the production of influenza virus in ReadyToProcess WAVE™ 25 bioreactor system
As shear stress is a critical parameter in virus production from anchorage-dependent cells, the possibility to increase working volume to 4 L, without increasing shear forces, was investigated. The re…
Article
Recombinant Adeno-Associated Virus Type 5 Production Process
A scalable recombinant adeno-associated virus (rAAV) type 5 production process was developed using transfected HEK293 suspension cells.
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Article
Virus and exosome purification: harness core bead technology
Using core bead technology to fine tune impurity removal and maximize recovery of
large entities.
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Article
Scalable ADCF Virus Production Using HyClone™ VaccineXpress Medium
The data show that the ADCF process using VaccineXpress for rotavirus propagation is scalable, promoting the production of infectious viral particles.
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Article
Case Study: Virus Reduction of an Affinity Capture Step
In this study, the virus reduction of an affinity capture step was evaluated in a scale-down column format. The study was performed by a third-party viral testing laboratory in collaboration with a bi…
Article
Concentration and Diafiltration of Cell-Derived, Live Influenza Virus Using 750 C Hollow Fiber Filter Cartridge
Cross flow filtration (CFF) is a technique extensively used in vaccine production and particularly in influenza vaccine manufacturing. In contrast to normal flow (dead-end) filtration (NFF), the fee…
Article
Production of Recombinant Adeno-associated Virus Vectors Using Microcarrier Culture of HEK293T Cells
As the gene therapy projects enter clinical Phase III or get market approval, large-scale production of viruses has become a limiting factor in the industrialization of gene therapy.
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Article
Viral Clearance Challenges in Bioprocessing
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Removal and inactivation of adventitious and endogenous viruses have traditionally been achieved during the downstream purification of biologics. Viral clearance is assessed in small-scale te…