Search results for "Surface plasmon resonance; SPR"

Article Applications of Surface Plasmon Resonance for Detection of Bispecific Antibody Activity
Surface plasmon resonance is helping define bispecific antibodies, the next-generation of biopharma therapeutics. By Robert Karlsson Abstract Biotherapeutic antibodies are still the larg…

Poster Performance of a fast Surface Plasmon Resonance based MAb quantification method
Monoclonal antibodies (MAb) are large complex molecules with many possible modifications that may affect safety and efficacy. Hence, many different analytical methods and techniques are needed to ch…

Article Real-Time Characterization of Biotherapeutics and Comparability of Biosimilars
Real-Time Characterization of Biotherapeutics and Comparability of Biosimilars A major advantage of SPR-based analysis is its ability to estimate the association and dissociation rate constants, an …

Article Bioterminology: A Guide to the Biopharmaceutical Lexicon
Bioterminology: A Guide to the Biopharmaceutical Lexicon This lexicon was generated by the editors of BioPharm International magazine. Please feel free to email your suggestions for terms that s…

Article Get Acquainted with How SPR Technology is Used for Better Protein Characterization
Surface plasmon resonance (SPR) has become a go-to tool for biotherapeutic characterization, and most approved antibody therapeutics have passed through a Biacore SPR system. Stay up-to-date wit…

Article Getting it Right from the Start in the Drug Development Process
Proper process understanding allows researchers to critically identify factors that impact the drug substance and product as well as minimize or maintain them at approved levels. As a result, the de…

Article Epitope Binning: A Critical Step in Antibody Selection
Read about how surface plasmon resonance (SPR) is used to characterize closely related “bins” of monoclonal antibodies (mAbs) targeting the same epitope of the target protein, and how the selection …

Poster High-Resolution SPR-Based Surrogate Potency Assay to Facilitate Comparability and Biosimilar Studies
An array of potency assays is needed to measure and monitor critical quality attributes (CQA) of antibody therapeutics. The poster shows how Biacore™ surface plasmon resonance (SPR)-based assays can b…

Article Ligand-Binding Assays and the Determination of Biosimilarity
During biosimilar development, it is necessary to demonstrate that the physicochemical properties, efficacy, and safety (e.g., immunogenicity) of the biosimilar are similar to those of the …

Article The Path to High-Quality Immunoassay Reagents
How Biacore surface plasmon resonance is shaping today’s assay development and selection of diagnostic reagents. Click here to learn more >>

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