Search results for "fermentation" in Articles / App Notes
Article
Fermentation for the Future
…s may be produced in much shorter times, according to Daniela Reinisch, a scientist responsible for fermentation technology with Boehringer Ingelheim RCV (BI). It is also useful for the production of…
Article
Scaling Up an E. coli Upstream Process for Plasmid DNA Production — from 2.5 to 160 L scale Fermenters
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This article summarizes the results of Escherichia coli growth performance for plasmid production in a 5 L glass fermentor, which was scaled up to 80 and 160 L scale in Xcellerex™ X…
Article
Stirring up the fermentation game
Microbial fermentation in single-use Xcellerex™ XDR-50 MO fermentor system
This application note describes the performance of a single-use Xcellerex XDR-50 bioreactor system when used in culti…
Article
Use of Multivariate Data Analysis in Bioprocessing
…an cell culture process for identification of batch homogeneity between lots and detecting abnormal fermentation runs (11). In similar work, researchers have succeeded in observing compositional chan…
Article
Being Thorough When Transferring Technology
This is particularly true for microbial fermentations. In the case of microbial fermentation, heating and mass transfer demands can often be controlled by the fed-batch feed rate. Thus, you want to us…
Article
Improving PAT for Biologics
Implementing PAT for bioprocesses presents unique challenges given the greater complexity of cell-culture and fermentation processes, the variability of raw materials (particularly living organisms), …
Article
Trends in Single-use Bioreactors
In addition, there are new systems now specifically designed for microbial fermentation.
Ang (Eppendorf): Most notable is the innovation of single-use bioreactors suitable for microbial fermenta…
Article
QbD and PAT in Upstream and Downstream Processing
Rathore (IIT Delhi): Typical CPPs for a fermentation step would be pH, sparge rate, agitation rate, and temperature. These are typically easy to control. Issues arise when one goes to volumes greater …
Article
What’s New in Upstream Technologies
Integrated online biomass measurement
Sartorius Stedim Biotech (SSB) added an integrated online biomass measurement to its ambr 15 fermentation and ambr 250 high throughput systems for microbial a…
Article
Performance of Single-Use Xcellerex™ XDR‑500 MO and XDR‑50 MO Stirred-Tank Fermentor Systems
Fermentations were performed as fed‑batch processes, with glycerol feed and a two‑stage induction strategy. The presented data was collected as foundational single‑use fermentation work, and can…