Search results for " HEK293"

Article Evaluation of HEK293 Cell Growth and Adenovirus Productivity in HyClone™ CDM4HEK293 Medium
This application note demonstrates growth of HEK293 cells in CDM4HEK293 medium in both shake flask and bioreactor cultures. Adenovirus productivity was evaluated in shake flask cultures. Performance i…

Article Evaluation of Hek293 Cell Growth and Adenovirus Productivity in HyClone CDM4HEK293 Medium
This application note demonstrates growth and adenovirus productivity of HEK293 cells and explores the key factors involved in the optimization of cell culture performance and scalability. Clic…

Article Production of Recombinant Adeno-associated Virus Vectors Using Microcarrier Culture of HEK293T Cells
As of March 2020, more than 4310 gene therapy clinical trials have been performed worldwide, with only 518 of them in Phase III and Phase IV. As the gene therapy projects enter clinical Phase III or g…

Article Biopharmaceutical Process Development: 2018 Lessons and 2019 Predictions
…escribing the development of downstream chromatography steps for the purification of adenovirus from HEK293 cell culture harvest. Single-Use Technologies Are Still Growing—But Not Without Challen…

Article Developing an Efficient Adenovirus Downstream Purification Process
This application note describes the development of downstream chromatography steps for purification of adenovirus from HEK293 cell culture harvest. To read the application note click her…

Article Achieving Efficient Adenovirus Upstream Production
This application note describes the production of adenovirus in HEK293 suspension cells in a bioreactor system. Triplicate cultures demonstrate a reproducible and robust batch production of adenovirus…

Poster Adenovirus production in a single-use stirring tank bioreactor system
In this work we demonstrate an efficient process for adenovirus production in a single-use stirred-tank bioreactor, using HEK293 cells adapted for suspension culture. Human adenovirus 5 expressing gre…

Poster Towards an optimized in-vitro SPR assay for antibody
Results using commercially available, recombinant extracellular FcgRs from two different expression systems, HEK293 (Sino Biological) and NS0 cells (R&D Systems), are presented. Click on the link …