Search results for "SPR"

Article Get Acquainted with How SPR Technology is Used for Better Protein Characterization
Stay up-to-date with our new e-book on the latest in SPR technology and use in the fields of process development and product quality control. Download the free e-book on Better Biotherapeutic Char…

Article Videos! SPR Applications in Protein Characterization
In these exclusive videos from the Biacore Analytical, Comparability and QC Symposium, Vienna, November 2017, industry thought-leaders share insights, tips, and techniques that illuminate how SPR with…

Poster Improving influenza vaccine quantification; a comparative study of SRID and SPR
In this study, a Biacore™ assay based on surface plasmon resonance-technology (SPR) was developed to achieve improved performance for concentration determination of the three human influenza virus typ…

Poster Towards an optimized in-vitro SPR assay for antibody
Therapeutic antibodies are now approved for a number of different indications. One important antibody (Ab) attribute is its Fc effector function, and Abs are now being engineered with the aim of obt…

Article Applications of Surface Plasmon Resonance for Detection of Bispecific Antibody Activity
By contrast, label-free technologies such as surface plasmon resonance (SPR) and bio-layer interferometry allow users to follow the dynamics of the interactions so that binding and dissociation events…

Article Ligand-Binding Assays and the Determination of Biosimilarity
SPR measures binding in terms of the “change in mass” that occurs as the ligand and binding partner attach to one another and then separate. Advances in SPR analysis have resulted in increased robustn…

Article Sensitive and Reproducible SPR-Based Concentration and Ligand-Binding Analyses
Surface plasmon resonance (SPR) assays are used across the life cycle of a biopharmaceutical, from target identification, through CQA determination, development, and on-going quality control. This art…

Article Impurity Testing of Biologic Drug Products
The same type of methodology can be applied to the evaluation of the most common post-translational modifications •  Liquid chromatography–mass spectrometry (LC–MS) or electrospray ioniza…

Poster High-Resolution SPR-Based Surrogate Potency Assay to Facilitate Comparability and Biosimilar Studies
The poster shows how Biacore™ surface plasmon resonance (SPR)-based assays can be used as surrogate potency assays to facilitate comparability and biosimilar studies (1). A capture-based assay that ca…

Poster Performance of a fast Surface Plasmon Resonance based MAb quantification method
In this work we show how Surface Plasmon Resonance (SPR) can be used for MAb quantification.

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