Search results for " concentration" in Posters
Poster
Optimization of concentration and diafiltration of a bovine γ-globulin solution
This application note describes the development of a cross flow filtration process for concentration of a bovine
γ-globulin solution.
Poster
Residual DNA analysis in influenza vaccine processing
Samples from the vaccine purification process contain different buffers, salts, and host cell compounds, and varies 3–4 logs in DNA concentration from harvest to the final product, which all put strai…
Poster
Development of DoE based fed-batch strategies for high-producing CHO cell cultures
Fed-batch culture is commonly employed to maximize cell and product concentrations in upstream mammalian cell culture processes. Typical standard platform processes rely on fixed-volume bolus feedin…
Poster
A Next Generation Protein A Chromatography Resin for Improved Productivity and Bioburden Control
mAb production using a Protein A capture step has followed a highly successful synergistic path the last 30 years. There are, however, remaining challenges.
• The increased upstream titers in mA…
Poster
Impact of sporicidal agent on MabSelect SuRe™ protein A resin lifetime
Bacterial endospore contamination constitutes a challenge in bioproduction due to their resistance to high concentrations of NaOH, commonly used in sanitization procedures. Hence, there is an intere…
Poster
Collaborating to address the bioburden challenge
For example, development of Protein A resins to withstand high NaOH concentrations and investigations of an oxidizing agent for sanitization are conducted.
Poster
Validation of Cytodex™ Gamma microcarrier-based virus production in single-use bioreactor systems
Cells in each WAVE Bioreactor system were infected with influenza virus and the concentration of infectious virus was determined by 50% tissue culture infective dose measurement. The results show viru…
Poster
Guide to modern BioProcess™ chromatography resins
Proteins are different. Based on what protein you would like to purify and the conditions used, chromatography resins are selected to optimize purity and yield. Many bioprocess applications include …