Search results for " resin"

Article Re-use of Protein A Resin: Fouling and Economics
The most significant contributor to the total cost is the Protein A resin. The cost of Protein A resin is nearly 50% higher than traditional chromatographic media with nonproteinaceous ligands (2, 10)…

Article Enhancing Resins Addresses Purification Concerns
Affinity chromatography resins such as oligo(dT) can be used as a capture step, but these resins are not able to separate single-stranded RNA (ssRNA) from double-stranded RNA (dsRNA), and they have a …

Article Comparing Protein A Resins for Monoclonal Antibody Purification
As a consequence, downstream processing must accept and handle higher titers of mAbs in harvested cell-culture fluid (HCCF), and vendors of mAb purification technologies must develop chromatography re…

Article Innovative Chromatography Resins Can Improve Purity and Quality
Recent advances in chromatography resins can effectively impact the purification unit operation with positive consequences that reverberate both upstream to the bioreactor and downstream to filtration…

Article Optimizing Resin Performance with Disposable Chromatography Solutions
The experts addressed how disposable chromatography columns can be used throughout the life of a campaign, the costs and benefits associated with using prepacked columns, the complexities of resin str…

Article Development and Future of Protein A Chromatography Technology: Q&A with Jonathan Royce, Business Leader Chromatography Resins, Cytiva
Although Protein A resins introduced to the market in the last 10 years withstand low to medium concentrations of sodium hydroxide for cleaning, like 0.1 M sodium hydroxide and in some cases 0.5 M, th…

Poster Evaluation of Protein A resin lifetime during extensive use (overloading) in continuous chromatography mode
This application note compares the performance of MabSelect SuRe pcc resin designed for continuous capture of mAbs, with the conventional high-capacity Protein A resin MabSelect SuRe LX. The study was…

Article Sanitization Opportunities for Protein A Resins
Several protein-based chromatography resins are also sensitive to such harsh sanitization conditions. As an alternative, the oxidizing agent peracetic acid (PAA) could be used in the control of such c…

Article Capto™ High Productivity Resins
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Article Five Reasons for Outsourcing Chromatography Resin Lifetime Studies
But are running these lengthy and repetitive studies the best use of your process development time? Discover the top five reasons for outsourcing resin reuse studies. Click here to read more >>

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