Search results for " 3D modeling"
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Mechanistic modeling quiz
Mechanistic models make it possible to create computer simulations of chromatograms. The simulations are based on physiochemical phenomena known to occur in chromatography. The benefit of a me…
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Advanced therapeutics process development using mechanistic modeling
Guterstam
Watch the interview of Peter Guterstam and Nick Whitelock (Cytiva), and learn about
the biological background of advanced therapeutics
what mechanistic modelling …
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Mechanistic vs Statistical Models
Mathematical models are recommended by the ICH Q8 guidelines on pharmaceutical development to generate enhanced process understanding and meet Quality-by-Design (QbD) guidelines. Read on the d…
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Benefits of DoE vs mechanistic modeling
Hear about the main differences between mechanistic modeling and design of experiments when used during chromatography process development. You will learn that, quite often, these methods work…
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Designing a 1.5 L Bench-Scale Model of a Perfusion Process
Establishing an appropriate model allows for higher throughput during simultaneous operation and monitoring of several cultures at different process conditions. In this article, we discus…
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Developing a Robust Bioprocess Using Mechanistic Models
The safety and efficacy of a biopharmaceutical drug are of the highest priority. Therefore, manufacturers have to design, implement and maintain measures to ensure that the bioprocess con…
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Do Modeling and Simulation Tools Really Benefit the Biosimilar Industry?
The business impact of modeling and simulation tools is not well understood and requires clarification of their benefits to drug development.
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Engage a mechanistic modeling expert – or become one
The application of mechanistic modeling requires expertise for effective use. When planning to implement this ground-breaking technology one essential question must be addressed befor…
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Mechanistic chromatography modeling in practice
Access insider recommendations for getting started with mechanistic modeling of chromatography, but also case studies and scientific publications.
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How do mechanistic chromatography models work?
This knowledge hub contains animations, articles, and webinars to explain what mechanistic modeling is, its benefits, and how it works.
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