Search results for " process economy"
Article
Process Chromatography: Continuous Optimization
“An increase in binding capacity will be beneficial for process economy reasons when purifying steadily increasing upstream titers,” he states. Current protein A resins are also exposed to feeds with …
Article
What is process development?
When added together, gains in productivity can have a big positive impact on process economy.
Fig 1. Biopharma process development is a balancing act.
Learn more…
Article
Downstream Processing for Cell-Based Therapies
By Qasim A. Rafiq, Fernanda Masri
With increasing numbers of advanced therapies—including cell and gene therapies—entering early- and late-stage clinical development, significant focus has been …
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Improving Process-Scale Chromatography
For example, Cytiva is currently using high-throughput screening techniques to screen hundreds of ligand designs with the goal of further improving process economy and robustness in mAb manufacturing …
Article
New Therapies Present Scaling Challenges
New Therapies Present Scaling Challenges
Manufacturing differences between traditional mAb therapies and newer biotherapeutics dictate whether processes should be scaled up, scaled out, or use an al…
Article
Overview of a scale-up of a cell-based influenza virus production process using ReadyToProcess equipment
This allows for an increase in the annual number of batches and multiproduct manufacturing, with an overall improved process economy as a result.
This case study shows that single-use equipment,…
Article
Reimagining Affordable Biosimilars
Advances in preclinical development play a crucial role in reducing cost for developing biosimilars.
By Anurag S. Rathore, Narendra Chirmule, and Himanshu Malani
Drug development is …
Article
Biopharma Advances Demand Specialized Expertise
Jun 15, 2015
By BioPharm International Editors
BioPharm International eBooks
Volume 28, Issue 13
Contract service providers share insights on biopharma market developments and the impl…
Article
Advancing Single-Use Technology Through Collaboration
By working together to harmonize the highly variable steps within the biopharmaceutical manufacturing process, both end users and suppliers are making strides toward the efficiency and integrity of …
Article
From Darwin to Recombinant Fc Multimers
IgG market will continue to dominate with 46% of market, followed by albumin, 18%, John Perkins stressed the importance of other plasma proteins to have a good process economy.
Some of the …