Search results for " process economy"
Article
Applications of Surface Plasmon Resonance for Detection of Bispecific Antibody Activity
During process development, the goals are to obtain high product yield and a good process economy; to ensure that properties related to initial CQAs are maintained; and to secure that the process itse…
Article
Innovative Chromatography Resins Can Improve Purity and Quality
…t development and manufacturing organizations (CDMOs) for process intensification, which can improve process economy and shorten time-to-market.
A generic capture step for mAbs and Fc fusion prot…
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Technical and Process Economical Aspects of Using Capto™ Q and ReadyToProcess™Adsorber Q in mAb Polishing
To identify scenarios for beneficial use of each of these product alternatives, a process economy simulation was conducted for two different process scales (500 and 2000 L).
View appllication note…
Article
Scalable Viral Vector Manufacturing
Finally, consider the process economy early in development. It is important to do process economy modelling at relevant production scales to ensure the commercial viability of your product.
Read m…
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Biopharma in 2015: A Year for Approvals and Innovations
Insiders agree that 2015 was a banner year for biopharma. Last year’s new drug approvals reached 51, besting every year since 1950. Twenty approvals (39%) went to biological drugs—up from 35% in 201…
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Process Economic Simulation for Scalable Production of Adenovirus
This application note discloses the process economic modelling of a modern start-to-finish adenovirus production process. The novel process was compared with a reference process in both stainless-st…
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Hybrid Bioprocessing: A Q&A with Andrew Sinclair
Process Development Forum speaks about hybrid bioprocessing with Andrew Sinclair, President and Founder of BioPharm Services
How would you define hybrid bioprocessing?
Hybrid processing is n…
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Comparing Protein A Resins for Monoclonal Antibody Purification
These results show that the use of Resin 3 in purification of antibodies from high-titer feeds significantly improves process economy (see Figure 2).
Summary
These data demonstrate that the Re…
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How to Adapt Biomanufacturing Processes
As the need for more complex molecules drives a new era of biomanufacturing, there is an increased focus on developing processes with improved security, yield, and process economy. Companies working…
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Evaluation of Performance of a Disposable mAb Affinity Chromatography Column Used Over Multiple Process Cycles
However, reuse of such columns could positively impact process economy. This application note demonstrates cycling of ReadyToProcess™ MabSelect SuRe™ LX columns in multiple process runs. Analysis of m…