Search results for "column packing" in Articles / App Notes

Article Unifying Continuous Biomanufacturing Operations
The success of a truly integrated continuous processing platform relies on the collaborative efforts of upstream and downstream specialists. By Randi Hernandez When human cells travel throug…

Article Analyzing Proteins Using SEC, MALS, and UHPLC
“Real proteins may be partially or completely disordered, contain significant hydrophobic residues that interact with column packing material in a non-ideal way, or perhaps be continuously heterogeneo…

Article Optimizing Cation-Exchange Chromatography with High-Throughput Process Development for mAb Purification
Optimization of each phase in a chromatographic cycle has a positive impact on productivity. By Anna Grönberg An important area of focus for the biopharma industry is the elucidation and dev…

Article HT Multi-Product Liquid Chromatography for Characterization of Monoclonal Antibodies
If used correctly, these new analytical methods can reduce analysis and product development time. ABSTRACT Monoclonal antibodies represent a significant portion of sales in the biopharma…

Article Reducing Cross-Contamination Risks in Process Chromatography
Preparatory and post-processing steps such as column packing, validation of packed-bed efficiency, verification of endotoxin clearance, unpacking, cleaning of unpacked columns, etc., can also be elimi…

Article Improving Process-Scale Chromatography
Advances in technology are increasing the productivity and efficiency of commercial-scale chromatography bioprocesses. By Cynthia Challener, PhD Chromatography is a crucial step in the purif…

Article Technology Innovations Improve Process Chromatography Performance
The performance reproducibility in column packing, which is essential for ensuring consistent scale-up, can accelerate technology implementation in manufacturing, says Hemanth Kaligotla, chromatograph…

Article Instructional Videos for Bioprocess Equipment
Modules also cover column packing and maintenance for pilot and process-scale columns. Each mediabook contains detailed videos for the equipment and the software interface. REGISTER HERE TO AC…

Article Using Digital Twins to Model Process Chromatography
Data on column packing quality [are] often available as part of column qualification, and conductivity transition data may provide an insight in fluid mechanics often overlooked. Data on buffer compos…

Article Setting Up Bioprocessing Systems for Digital Transformation
Hahn points out that, for instance, pre-packed single-use chromatography columns of the same type may differ in terms of column packing and resin lot capacity. “In practical application, these differe…

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