Search results for " platform"
Article
Diamyd Medical Selects Cytiva’s FlexFactory Platform to Make Precision Medicine Type-1 Diabetes Vaccine
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Diamyd Medical will install a new Cytiva FlexFactory platform in Umeå, Sweden. Once up and running, the clinical-stage biopharmaceutical company will begin manufactu…
Article
Platform for Purification of VHH-type Antibody Fragments
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Protein A affinity chromatography resins have been used to purify monoclonal antibodies (mAbs) by the bioprocess industry at all scales for a long time. Howev…
Poster
Purification platform challenges and strategies for handling of "tricky" MAbs
In the work presented here, capture using high-capacity protein A medium (resin) was followed by polishing using a novel cation exchange chromatography medium.
Article
Single-Use Technologies Prove Effective for Viral Vector Process Development
Adherent versus suspension cell culture
As mentioned, viral-vector producers have an initial choice between suspension and adherent production platforms. A key difference between adherent and su…
Article
Can Vaccine Development Be Safely Accelerated?
Several academic and industrial researchers have also focused on applying novel vaccine development and manufacturing platforms to the accelerated development of a COVID-19 vaccine.
In terms of…
Article
Addressing the Complex Nature of Downstream Processing with QbD
“In addition, the inherent high risk for drug failure at early stages of development combined with short development timelines suggests the need for a platform approach to manage the early phases of d…
Article
Emerging Therapies Test Existing Bioanalytical Methods
Platforms for gene- and cell-therapy programs
The choice of platform is primarily driven by and unique to the bioanalytical needs of the gene- and cell-therapy product under development. Specifi…
Article
Tools for Continuous Bioprocessing Development
• Standardization is hampered by use of various platforms and lack of design rules.
For instance, in cell culture, the typical biopharmaceutical company uses at least a dozen different platforms, …
Article
Strategizing for Rapid Changeovers in Biologics Manufacturing
…to be a cumbersome and costly process for multiproduct facilities, adds Piergiuseppe Nestola, senior platform technology consultant at Sartorius. “It is not unusual for changeover to require weeks to…
Article
Best Practices for Selecting a Top-Quality Cell Line
The challenge is to have a cell-line development platform that is robust and flexible enough to allow for troubleshooting across a broad range of production issues,” Fisch concludes.
Added to t…