Search results for "antibodies"

Article Witnessing Major Growth in Next-Generation Antibodies
Challener Next-generation antibodies are designed to be more specific and are often more potent than traditional monoclonal antibodies (mAbs). As a result, their commercial potential is significan…

Article Antibody Production in Microbial Hosts
Rathore, Jyoti Batra The biopharmaceutical industry is growing exponentially, driven by an ever-increasing demand for monoclonal antibodies (mAbs) and related products that are capable of treating…

Article Applications of Surface Plasmon Resonance for Detection of Bispecific Antibody Activity
By Robert Karlsson Abstract Biotherapeutic antibodies are still the largest growing class of medicines and are used globally to treat a wide range of diseases such as cancer, asthma, and rheum…

Article Single-Domain Antibodies for Brain Targeting
Smaller recombinant antibody fragments as single-domain antibodies (sdAbs) are emerging as credible alternatives because of their target specificity, high affinity, and cost-effective recombinant prod…

Article Generating a Fully Processed Antibody
Expression of tagged antibodies in the FGE clonal cell line The selected FGE line was used as the base cell line to express two different antibodies. The two antibodies bind to different targets w…

Article HT Multi-Product Liquid Chromatography for Characterization of Monoclonal Antibodies
ABSTRACT Monoclonal antibodies represent a significant portion of sales in the biopharmaceuticals market. Ever-growing biotechnology pipelines have greatly increased demand for higher throughput, …

Article The Development and Application of a Monoclonal Antibody Purification Platform
The following article describes the development of a purification platform for monoclonal antibodies (MAbs) at Pfizer's Global Biologics division, including how the individual unit operations have bee…

Article Chromatography for the Diversified Antibody Pipeline
Eva Helding: The antibodies are one of the largest classes of biomolecules and there are several approved drugs—the first approved drug was in 1986. The antibodies have been there; however, we have al…

Article Comparing Protein A Resins for Monoclonal Antibody Purification
The methodology for the production of monoclonal antibodies from a cell line by hybridization of mouse myeloma and mouse spleen cells from an immunized donor was first published in 1975 (1). As a tech…

Article Top Tips for Successful Development of Antibody Chromatography Processes
If we look back a couple of years, we saw that the main antibody group was monoclonal antibodies. But today, it's a lot more diverse. We see more fragments, such as Fabs, scFv fusion proteins, domain …

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