Search results for " cell"
Article
Taking a “Development-by-Design” Approach to Cell Therapies
In 2013, according to the Pharmaceutical Research and Manufacturers Association, 69 cell therapies, six of them autologous, or patient-specific treatments, were in clinical trials or being reviewed in…
Article
Cell-free Expression Systems Pose Cell Culture Alternative
Feliza Mirasol
Among the challenges in upstream bioprocessing is the cellular waste generated as a by-product of cell culture. One approach that potentially offers the benefit of a “cleaner”…
Article
Implications of Cell Culture Conditions on Protein Glycosylation
Richard Easton
This article reviews the implications of cell-culture conditions on biologic product quality, focusing on glycosylation and analytical techniques for its accurate assessment. Glyco…
Poster
Benchmarking, scalability, and protein production in CHO cell culture
With the large number of CHO clones in use, it is important to have a cell culture medium that supports high viable cell counts and productivity with multiple cell clones. A precise balance of nutri…
Article
FDA Seeks to Enhance Manufacturing of Cell and Gene Therapies
By Jill Wechsler
While cell- and gene-therapy products hold the promise of transforming the treatment of many diseases, difficulties in achieving consistent process control could sty…
Article
What’s in your media? How costly is variability of cell culture media to your manufacturing process?
Today we are going to discuss what is your media and how costly variability of the cell culture media is to the manufacturing process. I am Megan Manzano, senior editor for BioPharm Interantional. Joi…
Article
Fed-batch supplements to boost cell culture performance
This application note demonstrates the enhanced performance of commonly used cell lines for MAb production when supplemented with HyClone™ cell culture supplements. Cultures of Chinese hamster ovary (…
Article
Webinar: Establishing a CHO-K1 cell line and cell line development process for biotherapeutics markets
But how can you meet rapid timelines when the cell line development workflow is challenged by documentation needs, commercial use rights, and regulatory scrutiny?
Join Cytiva’s webinar on Febru…
Article
Cytiva and 4Tune Engineering Collaborate on Cell Therapy Quality Risk Management
…at they have entered into an agreement to include 4Tune Engineering’s iRISK platform in Cytiva’s cell therapy product offering.
Cytiva customers in the early stages of cell therapy product develop…
Article
Future-proof your AAV process with a complete producer cell line – just induce and grow
Ideally, everything needed to produce the required rAAV would be stably integrated in a single cell line. We describe such an all-inclusive cell line platform that can be customized for your specific …