Search results for "aav"

Article Insights and Strategies for Successful Development of Scalable AAV Processes: Part 2 of 2
Topics covered include: 1:00 – The upstream approach for AAV production, such as finding the balance between different parameters in the design of experiments to create a robust production proc…

Article Top Challenges to Overcome When Developing AAV Processes: Part 1 of 2
Topics covered include: 1:00 – Two main challenges for upstream AAV process development, including which development platform to use and scalability 3:09 – Parameters evaluated for AAV p…

Article Scalable AAV Production Process for Gene Therapy
Several viruses have been investigated for use in cell and gene therapy; adeno-associated virus (AAV) has emerged as the main vector for gene therapies. Here, we describe how we developed an efficient…

Article Cell culture process development for AAV vector production in suspension cells
Adaptation of HEK293 suspension cell line for transient transfection and scalable adeno-associated virus (AAV) production. READ FULL ARTICLE >>

Webcast The GMP of AAV: Purification for Clinical Production
Last, we’ll explore what’s on the horizon for systems and other purification techniques designed for purifying AAV according to good manufacturing practices (GMP) requirements.

Article The GMP of AAV: Purification for Clinical Production
Watch this presentation to learn about the key considerations when developing a purification process for adeno-associated viruses (AAV).  >>> Learn more

Article Successful Development of Scalable AAV Processes: Part 2 of 2
Watch the Q&A interview >> In the second of a two-part series, Anki Magnusson, Staff Research Engineer, Protein and Viral Production, and Åsa Hagner-McWhirter, PhD, Senior Scientist, Bio…

Article Top Challenges to Overcome When Developing AAV Processes: Part 1 of 2
Watch the Q&A interview >> In the first of a two-part series, Anki Magnusson, Staff Research Engineer, Protein and Viral Production, and Åsa Hagner-McWhirter, PhD, Senior Scientist…

Article How to Optimize and Scale Up AAV Production
In this article from a roundtable discussion, four experts from academia and industry met to discuss challenges in refining and scaling up AAV production pipelines to meet the increasing demand for …

Article Gene Therapies Push Viral Vector Production
By Feliza Mirasol  Several virus types have been studied for use as viral vectors in gene therapy, including adenovirus, lentivirus, retrovirus, and adeno-associated virus (AAV). Of these, AA…

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