Search results for " chromatography resin"

Article Process Chromatography: Continuous Optimization
Suppliers of chromatography resins are developing new resin chemistries and binding mechanisms to meet this need. Several interaction modes There are four major chromatographic techniques employed…

Article Making the Move to Continuous Chromatography
“Data indicate that more than one column offers better efficiency, and greater yield of product per unit volume of chromatography resin per unit of time. That means that because the columns are smalle…

Article Improving Process-Scale Chromatography
New resin chemistries New chromatography resins and chromatography ligands are constantly being developed, according to Lotta Ljungqvist, head of bioprocess R&D for GE Healthcare Life Sciences. Sh…

Article A Look at the Affinity Chromatography Landscape
The technology has also been used to develop chromatography resins for manufacturing of non-antibody biosimilars—such as FSH [follicle-stimulating hormone] and hCG [human chorionic gonadotropin]—and v…

Article Mixed-Mode Chromatography in Downstream Process Development
In summary, chromatography resins with multimodal ligands enabled us to purify a recombinant mutein of a protease inhibitor with an unusual solubility profile in a three-step process. Ligands combinin…

Article Process Chromatography Selection for Downstream Processing Applications
There is a continuous development of new chromatography resins combining separation modes. One example of this is the diffusion restricted Capto Core resin combining size exclusion with a functionaliz…

Article Optimizing Resin Performance with Disposable Chromatography Solutions
Although the initial uptake of single-use chromatography solutions has been relatively slow, an increased need for higher-capacity resins and the demand for smaller batches has made disposable chrom…

Article Technology Innovations Improve Process Chromatography Performance
The development of pressure stable chromatography resins, which allows seamless scale-up with high linear velocities, was another innovation that helped the industry address past chromatography challe…

Article Innovation in Pre-packed Disposable Chromatography Columns
GE’s share of the chromatography resins market is substantial, and contributes to their dominance of the pre-packed market, with around 55%. This share may be greater if resin revenues at retail level…

Article Reducing Cross-Contamination Risks in Process Chromatography
Reducing Cross-Contamination Risks in Process Chromatography Single-use systems provide replaceable fluid paths. By Cynthia A. Challener Fa…

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