Search results for "protein binding"

Article Polishing of Monoclonal Antibodies using Capto™ MMC ImpRes in Bind and Elute Mode
A rapid procedure to establish a robust second step in bind/elute (B/E) mode for the purification of a MAb using Capto MMC ImpRes has been developed. This study presents results from optimization …

Article Polishing of monoclonal antibodies using Capto adhere ImpRes in bind and elute mode
This application note describes a study where the binding capacity for MAbs and the efficiency in the clearance of impurities using Capto adhere ImpRes in bind/elute (B/E) mode was evaluated. For a …

Article How To Interpret Protein Binding Capacity: Chromatography Resins
Explore what protein binding capacity is, how it can be measured and what exactly to look for on a manufacturer’s specification sheet in this blog post. Read post

Article How to Determine Dynamic Binding Capacity (DBC) of Chromatography Resins
In protein purification, dynamic binding capacity (DBC) of a chromatography column describes the maximum amount of target protein that you can load onto your column without causing unnecessary loss, m…

Article Interpreting Protein Binding Capacities for Chromatography Resins
In this post, we explain what protein binding capacity is, how it can be measured, and what to look for on a manufacturer's specification sheet. Read more

Poster Polishing of Monoclonal Antibodies in Bind/Elute Mode Using Capto™ MMC ImpRes
This poster demonstrates a rapid procedure to establish a robust second step for the purification of a MAb using Capto™ MMC ImpRes in bind/elute mode. The results from optimization of the loading cond…

Tip How to screen for binding conditions with high-capacity ion exchangers
Some proteins exhibit unexpected behavior on ion exchangers that have been engineered for extra high binding capacity. For example, dynamic binding capacity for a specific molecule might increase wh…

Article Bioterminology: A Guide to the Biopharmaceutical Lexicon
Bioterminology: A Guide to the Biopharmaceutical Lexicon This lexicon was generated by the editors of BioPharm International magazine. Please feel free to email your suggestions for terms that s…

Article Re-use of Protein A Resin: Fouling and Economics
Mar 01, 2015 By Anurag S. Rathore, Mili Pathak, Guijun Ma, Daniel G. Bracewell BioPharm International Volume 3, Issue 28 In the past two decades, Protein A affinity chromatography ha…

Article Optimization of Protein Expression in Escherichia Coli
May 01, 2015 By Siavash Bashiri, David Vikström, Nurzian Ismail BioPharm International Volume 28, Issue 5 Production of proteins for manufacturing therapeutics and pharmaceuticals is a c…

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