Search results for " process economy"

Poster Scale-up and process economy calculations of a dAb purification process using ready-to-use products
In addition, process economy of using ready-to-use equipment and ready-made buffers versus using reusable equipment and in-house prepared buffers was compared. A three-step dAb purification process wa…

Poster Process economy and production capacity using single-use versus stainless steel fermentation equipment
This white paper compares production capacity and process economy between stainless steel and single-use equipment in microbial processes. Economy simulations were based on an E. coli Dab process. P…

Poster Case Study: Improve Process Economy by Cycling of Prepacked Chromatography Columns
The use of disposable technologies in downstream processing has increased significantly over the last years, as they reduce the need for time-consuming cleaning and cleaning validation operations as…

Article Process Economy Simulations on a Protein A Capture Step
MabSelect PrismA is a next‐generation protein A chromatography resin that offers significantly enhanced alkaline stability and capacity compared with its predecessor products. This application note …

Poster Process Economy Impact of Protein A Resin Alkaline Stability
This poster presents a process economy simulation comparing three protein A chromatography resins with the aim to demonstrate the influence of dynamic binding capacity (DBC) and alkaline-stability of …

Poster Process economy effects of modernizations in vaccine purification
The vaccine industry is currently considering modernization of old, legacy processes. Old purification steps are being made obsolete by introducing modern purification techniques, aiming for increas…

Poster Process economy modeling for viral vector production
Here we used an alternative strategy: start with process economy calculations, and let the outcome guide to which unit operations would be economically feasible, and should be the primary focus of the…

Article Economic drivers and trade-offs in antibody purification processes
The future of therapeutic MAbs lies in the development of economically feasible downstream processes.  By Suzanne S. Farid, PhD  ABSTRACT Increasing titers in mammalian cell culture has rec…

Article Regulatory Challenges in the QbD Paradigm
The authors demonstrate how an integrated model is helping to achieve regulatory flexibility. This article is part of a special section on biopharmaceutical trends. With the dawn of the 2…

Article Achieving Process Balance with Perfusion Bioreactors
Advances in single-use technologies, sensors, and cell retention systems facilitate processes designed for the long run. By Cynthia A. Challener  MG/Stock.Adobe.com …

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