Search results for " capture"

Webcast Strategies and emerging technologies for mAb capture
Strategies will depend on the mode of upstream operations (fed batch or perfusion) and the desired process improvement of the capture step, e.g., productivity, cost, or process time, as well as the ty…

Article Strategies and Emerging Technologies for mAb Capture
Strategies will depend on the mode of upstream operations (fed batch or perfusion) and the desired process improvement of the capture step, (e.g., productivity, cost, or process time) as well as the t…

Article Optimizing capture and polishing steps in an rAAV purification process
The chromatography purification described includes affinity capture to maximize recovery with efficient impurity removal. READ FULL ARTICLE >>

Article Case Study: Virus Reduction of an Affinity Capture Step
In this study, the virus reduction of an affinity capture step was evaluated in a scale-down column format. The study was performed by a third-party viral testing laboratory in collaboration with a bi…

Article Multidimensional Scale-Up of a Monoclonal Antibody Capture Step, Using ÄKTA™ pilot 600
In this work, a multidimensional scale-up (change of both column diameter and bed height) of a mAb capture step, using the ÄKTA pilot 600 chromatography system, is demonstrated. Column volume per…

Resource Strategies and Emerging Technologies for mAb Capture
20 May 17 CEST | 11 EDT

Article Process Economy Simulations on a Protein A Capture Step
MabSelect PrismA is a next‐generation protein A chromatography resin that offers significantly enhanced alkaline stability and capacity compared with its predecessor products. This application note …

Article Evolution of the Monoclonal Antibody Purification Platform
Typical steps include: • Protein A chromatography for capture of the product and removal of host cell-related impurities (host cell proteins and DNA). Though extremely efficient and effective,…

Article Successfully Moving Regulated Data to the Cloud
The document provides clarification on how data should be captured to most effectively preserve its integrity, primarily in the current good manufacturing practice (CGMP) regulated space (1). The d…

Article Improving Process-Scale Chromatography
The development of new resin chemistries including enhancements to Protein A for monoclonal antibody (mAb) capture, increasing use of automation, implementation of single-use technologies, and explora…

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