Search results for " upstream"

Article QbD and PAT in Upstream and Downstream Processing
UPSTREAM PROCESSING BioPharm: In implementing QbD, what would you identify as the critical quality attributes (CQAs) in a typical upstream bioprocess using cell-culture? Vanden Boom (Hosp…

Article Automating Processes in Upstream Processing
BioPharm: What specific challenges do companies face when automating upstream processes? Marshall: New product introductions into existing facilities often require new equipment process capabiliti…

Article What’s New in Upstream Technologies
The system features a modular, scalable, fixed-bed bioreactor for enhanced upstream processing of viral products, including viral vaccines, viral vectors, and oncolytic viruses. The low-footprint inte…

Article Achieving Efficient Adenovirus Upstream Production
Adenovirus is one of the most frequently used viral vectors in the development of therapeutic vaccines and vaccines against infectious diseases. Adenovirus has also been explored as a viral vector f…

Article Optimized Process Efficiency in Upstream Manufacturing
Process efficiency is a key goal for biopharmaceutical production. Click here to learn how faster cell-line development, real-time analytics, and other approaches can be used to create a flexi…

Poster Integration of continuous upstream and downstream operations in mAb production
For a competitive production process, continuous or semi-continuous upstream and downstream processing can be employed. Compared with a process performed in batch runs, continuous processing allows fo…

Article Upstream, Downstream Processing in Motion
The platform, available globally, incorporates both upstream and downstream steps, including chromatography systems that use fully disposable single-use flow paths, prepacked and prequalified chromato…

Upstream

Article Unifying Continuous Biomanufacturing Operations
The most efficient upstream processing systems in biologics manufacturing seek to mimic the body’s treatment of cells, so a constant level of incoming nutrients and outgoing waste products is necessar…

Article Continuous Processing for the Production of Biopharmaceuticals
The industry already has experience in terms of continuous upstream processing. Perfusion technology has been successfully used for the production of biotherapeutics for more than a decade. In the pas…

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