Search results for " cell growth"
Article
Evaluation of HEK293 Cell Growth and Adenovirus Productivity in HyClone™ CDM4HEK293 Medium
Human embryonic kidney 293 (HEK293) cells are widely used in production of recombinant viruses and proteins because of their stable growth, high transfection level, and ability to produce high viral t…
Poster
Scale-up of CHO fed-batch cultures in HyClone™ ActiPro™ medium supplemented with Cell Boost™ 7a and 7b
Comparing cell growth and recombinant protein production of multiple Chinese hamster ovary (CHO) cell clones when cultured in HyClone ActiPro basal medium and Cell Boost 7a and 7b feeding supplement…
Article
Perfusion Culture Using TFF or ATF as Cell Retention Method
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Perfusion processes have many advantages such as being favorable for product quality and supporting efficient facility utilization by offering the possibility…
Poster
Effects of feeding strategy on CHO cell performance in fed-batch cultures
The results emphasize the importance of an appropriate feeding strategy to achieve optimal cell growth and productivity.
Article
Evaluation of Hek293 Cell Growth and Adenovirus Productivity in HyClone CDM4HEK293 Medium
This application note demonstrates growth and adenovirus productivity of HEK293 cells and explores the key factors involved in the optimization of cell culture performance and scalability.
Cli…
Poster
Development of a chemically defined medium for virus vaccine production in a duck suspension cell line
A project was initiated to improve the production process for viral vaccines through the use of the EB66® cell line derived from duck embryonic stem cells and proprietary to Valneva. The primary goa…
Article
Impact of Media Components on CQAs of Monoclonal Antibodies
Intense efforts in bioprocess development have been made to improve the production of CHO-based biopharmaceuticals by cell line engineering, improved methods for cell growth, and upregulating the post…
Article
Generating a Fully Processed Antibody
…ugh levels to fully process all the biopharmaceutical at high titers without interfering with normal cell growth and the secretion of the molecule. Finally, some multispecific antibody platforms requ…
Article
Implementation of Raw Material Control Strategies in the Manufacture of Single-Use Bioprocessing Containers
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This article discusses efforts to limit polymer degradation without significantly impeding cell growth. The authors were able to show that a single resin can be converted to films that lead…
Article
New Therapies Present Scaling Challenges
New Therapies Present Scaling Challenges
Manufacturing differences between traditional mAb therapies and newer biotherapeutics dictate whether processes should be scaled up, scaled out, or use an al…