Search results for "filtration"
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Instructional Videos for Bioprocess Equipment
Cytiva offers free on-demand instructional videos that will help you with operating bioreactors, chromatography and filtration systems, including flow kit installation on single-use systems. Modules a…
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Digitalization: The Route to Biopharma 4.0
For formulation, a model for predicting volumetric concentration factor across single pass tangential flow ultrafiltration (SPTFF) can be used to develop real-time automated monitoring and a control s…
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High-concentration monoclonal antibody drugs: manufacturing challenges
Manufacturing unit operations that are directly impacted by higher concentration formulations range from ultrafiltration to sterile filtration, filling, mixing and storage. Solutions that maintain qua…
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Technology Innovations Improve Process Chromatography Performance
…rated with other product flow-through purification steps, such as anion exchange polishing or virus filtration, without requiring conductivity adjustment or dilution.”
While some bioprocessing is…
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Eliminating Residual Impurities Starts with a Strategic Plan
The selected isolation method—precipitation, filtration, centrifugation, extraction, etc.—should not affect the impurities with respect to concentration or composition. If derivatization is necessary …
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Next Generation Bioprocesses: Mapping Roads to the Future
In downstream processing, it can be intensified capture, in-line virus inactivation, flow through polishing, in-line virus filtration, or single-pass filtration.
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A Plastic Pipeline for Commercial Bioprocessing?
More than 75% use filled media bags, preassembled tubing sets, depth filters, bioreactors, sampling systems, and tangential flow filtration devices. Less than two-thirds use disposable chromatography …
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Integrated Semi-Continuous Process for mAb Production
In brief, the mAb process consists of perfusion cell culture, continuous capture chromatography, viral inactivation (VI), post VI filtration, batch polishing chromatography, and a final pH adjustment …
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The Challenge of Disruptive Technologies in Bioprocessing
A salt-tolerant resin can be beneficial to a purification process by decreasing the need for dilution or eliminating tangential flow filtration steps all together. In addition, there has been increase…
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Bioburden Control in the Biopharmaceutical Industry
Field, “Bioburden Control at the Sterile Filtration Step: A Risk-Based Approach,” presentation to European Biopharmaceutical Enterprises (May 2013).
10. Critical Process Filtration Inc., “Partic…